Metabolism Xagena

Poor sleep quality may be associated with osteoporosis

The aim of the present study was to investigate the impact of sleep on osteoporosis.

The study used a baseline examination of the Hiroshima Sleep and Healthcare study, which was a cross-sectional and cohort study that addressed the association of sleep habits with lifestyle-related diseases.

A total of 1032 participants ( 25-85 years of age ) who underwent health examinations were included.

Sleep habits, including its timing ( bed time ), quantity ( time in bed [ TIB ] ), and quality, were assessed using the Pittsburgh Sleep Quality Index ( PSQI ).
The bone stiffness index ( SI ), a marker of osteoporosis, was measured using quantitative ultrasound systems.

Bed time ( r = 0.065, p  less than 0.05 ), TIB ( r = -0.064, p  less than 0.05 ), and global PSQI score ( r = -0.126, p  less than 0.0001 ) significantly correlated with SI.

Multiple regression analyses revealed that after adjusting for age, sex, body mass index, smoking, and alcohol intake, the global PSQI score ( β = -0.053, p  less than 0.05 ) was significantly associated with SI, whereas bed time or TIB was not.

Among each component of PSQI, sleep disturbances ( β = -0.084, p  less than 0.005 ) were significantly associated with SI.

In conclusion, poor sleep quality may be associated with osteoporosis. In particular, increased sleep disturbances may be a key factor in the association between poor sleep quality and osteoporosis. ( Xagena )

Sasaki N et al, Sleep Med 2016; 25: 73-77