AKCEA-APOCIII-LRx and reductions in triglycerides and atherogenic lipoproteins
A phase 2 study reported dose-dependent reductions in triglycerides and apoC-III with a favourable safety profile.
Latest research updates
Metabolism News is an English-language archive of research summaries on diabetes, lipid disorders, obesity, osteoporosis and cardiometabolic health. Articles are provided for general information and do not replace individual medical advice.
Durable LDL-cholesterol reduction with Inclisiran
Pooled phase III analyses evaluated the efficacy and safety of Inclisiran for hyperlipidaemia.
Medications associated with risk of developing osteoporosis
A study evaluated patterns in the use of medicines associated with an increased risk of osteoporosis.
Long-term safety and efficacy of Alirocumab in heterozygous familial hypercholesterolaemia
An open-label extension examined Alirocumab in patients receiving maximally tolerated statin therapy.
Abaloparatide, bone density and fracture risk in older women
Trial data examined bone mineral density and fracture outcomes in postmenopausal women aged 80 years or older.
Individualised LDL-cholesterol reduction with Alirocumab titration
An extension study assessed an individualised Alirocumab strategy in heterozygous familial hypercholesterolaemia.
Combination therapy for osteoporosis and bone mineral density
Research compared combination therapy with anabolic treatment alone for bone mineral density outcomes.
Gut bacteria and metabolic disease, including type 2 diabetes
A study explored the association between metabolic disease and bacteria that penetrate the colonic mucus layer.
Adolescent obesity and risk of heart disease
Research linked obesity in adolescence with a higher risk of heart disease in early adulthood.
Poor sleep quality and osteoporosis
A cross-sectional study explored the relationship between sleep quality and osteoporosis.
Dietary magnesium and reduced cardiometabolic risk
A meta-analysis examined dietary magnesium in relation to heart disease, stroke and type 2 diabetes.