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Prolia ( Denosumab ) is designed to inhibit RANKL ( RANK ligand ), a protein that acts as the primary signal for bone removal. Activation of RANK by RANKL promotes the maturation of pre-osteoclasts in ...


Patients with heart disease in Norway, a country with no fortification of foods with Folic acid, had an associated increased risk of cancer and death from any cause if they had received treatment with ...


Patients who take glucocorticoid drugs ( such as Prednisolone or Prednisone ) to treat a variety of inflammatory/immune-mediated diseases ( such as rheumatoid arthritis or asthma ) can suffer side eff ...


Researchers found patients with glucocorticoid-induced osteoporosis who were treated with Teriparatide ( Forteo, Forsteo ) for 36 months had a greater increase in bone mineral density ( BMD ) and fewe ...


Twice-yearly treatment with Denosumab ( Prolia ) has increased bone density and prevented spinal fractures in men receiving androgen-deprivation therapy for prostate cancer.The report is published in ...


European Medicines Agency ( EMEA ) has completed a review of Rimonabant ( Acomplia ) after concerns about its psychiatric safety. Thereview has found that the benefits of Rimonabant do not outweigh th ...


A healthy lifestyle during the early elderly years, including weight management, exercising regularly and not smoking, may be associated with a greater probability of living to age 90 in men, as well ...


Alendronate ( Fosamax ), a medication used to prevent fractures in women with osteoporosis, may be associated with an increased risk of atrial fibrillation. Other recent studies have reported atria ...


Researchers at Cleveland Clinic have recently completed a pair of studies to determine the safety and efficacy of a new, potent type of cholesterol treatment known as a peroxisome proliferator-activat ...


Researchers at Georgetown University Medical Center have been able to use simple, non-toxic chemical injections to add and remove fat in targeted areas on the bodies of laboratory animals. They say th ...


Premenopausal women who were assigned to follow the Atkins diet for one year lost more weight when compared to women who were assigned to follow the Zone, Ornish and LEARN diets. Overweight and obe ...


A study found that obesity increases the risk of death from prostate cancer, even though it does not increase the overall risk a man will be diagnosed with the disease. The study has shown that high ...


Researchers, at Albert Einstein College of Medicine of Yeshiva University, looked for genetic clues to longevity in a group of 214 Ashkenazi Jews who have passed or nearly reached 100 years of age. T ...


A study by Queen's University researchers has shown that visceral fat in the abdomen is directly associated with a higher risk of mortality in men. According to Jennifer Kuk, who is the first auth ...


Reducing calories over six months resulted in a decrease in fasting insulin levels and body temperature, two biomarkers of longevity. Prolonged calorie restriction increases life span in rodents a ...