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Results from a prospective study have shown that patients with a body mass index ( BMI ) in the obese range live on average two to three months less after a pancreatic cancer diagnosis, compared with ...


Sanofi and Regeneron Pharmaceuticals have announced that the Phase 3 ODYSSEY MONO trial with Alirocumab, an investigational monoclonal antibody targeting PCSK9 ( proprotein convertase subtilisin/kexin ...


Merck ( MSD ) has announced that the HPS2-THRIVE ( Heart Protection Study 2-Treatment of HDL to Reduce the Incidence of Vascular Events ) study of Tredaptive ( extended-release Niacin / Laropiprant ) ...


Two clinical studies were conducted to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and potential immunogenicity of single and multiple escalating doses ( IV [ intravenous ] an ...


The results from a phase II trial for Odanacatib, a cathepsin K ( cat-K ) inhibitor in development for the treatment of osteoporosis in post-menopausal women, were presented at the 34th Annual Meeting ...


La Food and Drug Administration ( FDA ) has approved a new indication for Prolia ( Denosumab ) as a treatment to increase bone mass in men with osteoporosis at high risk for fracture. Prolia, the firs ...


The emerging idea that obesity may have an infectious origin gets new support in a cross-sectional study by University of California San Diego School of Medicine researchers who found that children ex ...


Home-based exercises followed by voluntary home training seem to be associated with long-term effects on balance and gait, and may help protect high-risk, elderly women from hip fractures, according t ...


Prolia ( Denosumab ) is designed to inhibit RANKL ( RANK ligand ), a protein that acts as the primary signal for bone removal. Activation of RANK by RANKL promotes the maturation of pre-osteoclasts in ...


Patients with heart disease in Norway, a country with no fortification of foods with Folic acid, had an associated increased risk of cancer and death from any cause if they had received treatment with ...


Patients who take glucocorticoid drugs ( such as Prednisolone or Prednisone ) to treat a variety of inflammatory/immune-mediated diseases ( such as rheumatoid arthritis or asthma ) can suffer side eff ...


Researchers found patients with glucocorticoid-induced osteoporosis who were treated with Teriparatide ( Forteo, Forsteo ) for 36 months had a greater increase in bone mineral density ( BMD ) and fewe ...


Twice-yearly treatment with Denosumab ( Prolia ) has increased bone density and prevented spinal fractures in men receiving androgen-deprivation therapy for prostate cancer.The report is published in ...


European Medicines Agency ( EMEA ) has completed a review of Rimonabant ( Acomplia ) after concerns about its psychiatric safety. Thereview has found that the benefits of Rimonabant do not outweigh th ...


A healthy lifestyle during the early elderly years, including weight management, exercising regularly and not smoking, may be associated with a greater probability of living to age 90 in men, as well ...